IC4O, IC43 - what's the role of this chip in the design?
What's the function of IC40/43 (other than driving the 50R load switch in a 'fancy' way?)? Is it to default the termination to ON if the FPGA is not driving the termination enable pin? If so, why not use a diode and a pullup resistor? It should also simplify the routing as the switch needs symmetric 11V power.